How long does the effect of the HiFu procedure last and how does it develop over time?

HiFu (High-Intensity Focused Ultrasound) therapy is a non-invasive cosmetic procedure known for its lifting effect and its ability to stimulate the production of new collagen. Unlike other superficial therapies, HiFu acts in the deep layers of the skin and activates the body's natural regenerative processes. The effect of the HiFu procedure can be observed gradually, developing over time and depending on a number of individual factors. But when exactly do visible results begin to appear and how long do they last? In this article, we will look at how the effect develops after HiFu therapy and what scientific research says on the subject.

What happens immediately after the procedure?

Immediately after the HiFu procedure, some patients notice a slight lifting or firmer appearance of the skin. This effect of the HiFu procedure is due not to the true impact of the therapy, but to two physiological processes:

• Thermal shrinkage of collagen fibers – at a temperature of around 60-70°C, collagen structures temporarily shorten.
• Local edema – the inflammatory response after the procedure creates a feeling of volume and tightness.

These initial changes are temporary. The true impact of HiFu begins days and weeks later.

See also: What causes the immediate effect after a HiFu procedure?

How long does it take for the real effect to start?

HiFu activates the process of neocollagenesis – the formation of new collagen and elastin. This is done by stimulating fibroblasts in the dermis and in the SMAS (Superficial Musculoaponeurotic System) layer, which is the same layer targeted in a surgical facelift.

Effect timeline:

According to a systematic review of clinical studies and meta-analyses, the effect usually lasts between 12 and 18 months, and with supportive therapies and good habits – up to 24 months.

What affects the duration?

• Age and skin condition – the skin in younger patients with good regeneration retains the effect longer Lux Medical Aesthetic Clinicacademic.oup.com.
• Treatment area – face and neck typically maintain results for 12-18 months; for the body (abdomen, thighs), maintenance therapies can extend the effect up to 24 months.
• Quality of the device and the specialist's technique – precise tuning and experience significantly improve the long-term effect academic.oup.com.

Scientific support:

• Systematic review (Lasers in Medical Science, 2020): establishes safety and moderate effectiveness for face and neck lifting, but points to lack of long-term follow-up combined link.springer.com.
• Aesthetic Surgery Journal, July 2025: includes 45 clinical studies showing an improvement in firmness with 18-30%, and a reduction in body circumference by 2.5-4.5 cm. The effect is stable for up to 24 months with maintenance.